Protein Chromatography: Process Development and Scale-Up by Giorgio Carta, Alois Jungbauer

Protein Chromatography: Process Development and Scale-Up



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Protein Chromatography: Process Development and Scale-Up Giorgio Carta, Alois Jungbauer ebook
Publisher: Wiley, John & Sons, Incorporated
Format: pdf
Page: 364
ISBN: 3527318194, 9783527318193


Ion-Exchange Chromatography of Proteins, Shuichi Yamamoto, Kazuhiro Naka- .. Process Development is a series of predefined experiments to identify critical variables in a process and determine how these variables may influence scale-up [6.6]. High-throughput process development (HTPD) shortens development time, while the ÄKTA platform enables optimization, further characterization and scale-up. QbD and PAT based process development for chromatographic steps for a Process scale-up from pilot scale to clinical scale and from clinical to commercial scale selectivity enhancers in electrophoretic separation of proteins and peptides. Ceramic Hydroxyapatite Application Guide for Process Development and Scale-Up. Important constraint to the successful scale-up of a 'chromatographic system. Protein chromatography: process development and scale-up - Scholars Portal Books. 1.5.2 The WGFE Manufacturing Process 9. 6.6 PDA Journal of Pharmaceutical Science and Technology, Technical Report #42, Process Validation of Protein Manufacturing, Supplement Volume 59, pages 3-7, September/October 2005. Booktopia has Protein Chromatography, Process Development and Scale-Up by Giorgio Carta. The basic premise for scaling up a centrifugation process is to keep the .. The agreement will incorporate a process -development and scale-up phase in order to produce material suitable for clinical trials and to determine the compatibility with Cangene's manufacturing processes. Cangene is one of Canada's largest and earliest biopharmaceutical companies and Denmark-based Upfront Chromatography's develops customized industrial-scale protein chromatography processes. It is an essential step leading up to formal process validation and . Limited by the availability of protein properties capable of describing essential parameters in the complex scale-up methodologies for chromatographic systems have been developed.